Purine-rich element binding protein B attenuates the coactivator function of myocardin by a novel molecular mechanism of smooth muscle gene repression

Myocardin is a potent transcriptional coactivator protein, which features as the grasp regulator of vascular smooth muscle cell differentiation. The cofactor exercise of myocardin is mediated by its bodily interplay with serum response issue, a ubiquitously expressed transactivator that binds…