Cullin 1 human protein and gene

pd-1 pd-l1

PD-1/PD-L1 inhibitor 1
B6172-5 5 mg
EUR 168
Description: IC50: 0.006-0.10 ?MPD-1/PD-L1 inhibitor 1 is a PD-1/PD-L1 interaction inhibitor.Plenty of studies show that blocking the PD-1/PD-Ll interactions can lead to the restorage and augment of T cell activation in many systems.

PD-1/PD-L1 Inhibitor 1
B1213-25
EUR 566

PD-1/PD-L1 Inhibitor 1
B1213-5
EUR 185

PD-1/PD-L1 inhibitor 2
B6023-25 25 mg
EUR 438
Description: PD-1/PD-L1 inhibitor 2 is a PD-1/PD-L1 interaction inhibitor.

PD-1/PD-L1 inhibitor 2
B6023-5 5 mg
EUR 171
Description: PD-1/PD-L1 inhibitor 2 is a PD-1/PD-L1 interaction inhibitor.

PD-1/PD-L1 Inhibitor 2
B1050-25
EUR 566

PD-1/PD-L1 Inhibitor 2
B1050-5
EUR 202

PD-L1, CD274
E6TA00108 0.1mg
EUR 343

PD-L1 Protein
20-abx261703
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

PD-L1 Protein
20-abx263458
  • EUR 1609.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 10 ug
  • 2 µg

PD-L1 Antibody
P1013-1ml 1ml
EUR 673

PD-L1 Antibody
P1013-01m 0.1m
EUR 187

PD-L1 Antibody
49251-100ul 100ul
EUR 333

PD-L1 Antibody
49251-50ul 50ul
EUR 239

Anti-PD-L1
DB-241-0.1 100 μl
EUR 391
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-PD-L1
DB-241-0.2 200 μl
EUR 563
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-PD-L1
DB-241-0.5 500 μl
EUR 741
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-PD-L1
DB-241-RTU-15 15 ml
EUR 678
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-PD-L1
DB-241-RTU-7 7 ml
EUR 433
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-PD-L1
DB241-RTU-15 15 ml
EUR 678
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-PD-L1
DB241-RTU-7 7 ml
EUR 433
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

PD-L1 Antibody
4059-002mg 0.02 mg
EUR 171.82
Description: PD-L1 plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, PD-L1 modulates the activation threshold of T-cells and limits T-cell effector response (1). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (2,3). Through a yet unknown activating receptor, it may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (4).

PD-L1 Antibody
4059-01mg 0.1 mg
EUR 436.42
Description: PD-L1 plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, PD-L1 modulates the activation threshold of T-cells and limits T-cell effector response (1). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (2,3). Through a yet unknown activating receptor, it may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (4).

PD-L1 Peptide
46-156P 0.1 mg
EUR 338
Description: CD274 / PD-L1 Peptide

PD-L1 Peptide
4059P 0.05 mg
EUR 164.75
Description: (IN) PD-L1 peptide

B7-H1/PD-L1
E21-315 10ug
EUR 343

PD-L1 Rabbit pAb
A11273-100ul 100 ul
EUR 308

PD-L1 Rabbit pAb
A11273-200ul 200 ul
EUR 459

PD-L1 Rabbit pAb
A11273-20ul 20 ul
EUR 183

PD-L1 Rabbit pAb
A11273-50ul 50 ul
EUR 223

PD-L1 Rabbit pAb
A1645-100ul 100 ul
EUR 308

PD-L1 Rabbit pAb
A1645-200ul 200 ul
EUR 459

PD-L1 Rabbit pAb
A1645-20ul 20 ul
EUR 183

PD-L1 Rabbit pAb
A1645-50ul 50 ul
EUR 223

PD-L1 Blocking Peptide
20-abx161326
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

Anti-PD-L1 antibody
STJ130022 50 µl
EUR 321
Description: Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and nonhematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PDL1 has become an important biomarker and immunotherapy target for many types of malignancies.

Anti-PD-L1 antibody
STJ130023 50 µl
EUR 321
Description: Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and nonhematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PDL1 has become an important biomarker and immunotherapy target for many types of malignancies.

Anti-PD-L1 antibody
STJ130024 50 µl
EUR 321
Description: Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and nonhematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PDL1 has become an important biomarker and immunotherapy target for many types of malignancies.

Anti-PD-L1 antibody
STJ180217 0.1 ml
EUR 280

Anti-PD-L1 antibody
STJ180383 0.1 ml
EUR 246

Anti-PD-L1 antibody
STJ190082 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to PD-L1 (AS1A7)

Mouse PD-L1 Antibody
32903-05111 150 ug
EUR 261

PD-L1 (CD274) siRNA
20-abx910978
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

PD-L1 (CD274) siRNA
20-abx910979
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

PD-L1 Conjugated Antibody
C49251 100ul
EUR 397

PD-L1 Rabbit mAb
A20270 20 μL
EUR 15

PD-L1 Rabbit mAb
A20344 20 μL
EUR 15

Anti-PD-L1 Antibody
A1454-100
EUR 338

Anti-PD-L1 Antibody
A1454-30T
EUR 146

PD-L1 Recombinant Protein
96-937 0.1 mg
EUR 516.5
Description: Programmed cell death 1 ligand 1 (PD-L1) is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. B7-H1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. PD-L1 is highly expressed in the heart, skeletal muscle, placenta and lung and weakly expressed in the thymus, spleen, kidney and liver. PD-L1 is expressed on activated T-cells, B-cells, dendritic cells, keratinocytes and monocytes. PD-L1 is up-regulated on T- and B-cells, dendritic cells, keratinocytes and monocytes after LPS and IFNG activation and up-regulated in B-cells activated by surface Ig cross-linking. PD-L1 involve in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.

PD-L1 Recombinant Protein
97-020 0.1 mg
EUR 595.25
Description: Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

PD-L1 Antibody [F6A9]
SD8639-002mg 0.02 mg
EUR 211.02
Description: PD-L1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.

PD-L1 Antibody [F6A9]
SD8639-01mg 0.1 mg
EUR 603.02
Description: PD-L1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.

PD-L1 Antibody [F2G2]
SD8641-002mg 0.02 mg
EUR 211.02
Description: PD-L1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.

PD-L1 Antibody [F2G2]
SD8641-01mg 0.1 mg
EUR 603.02
Description: PD-L1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.

Back to top