DNA damage-signaling, homologous recombination and genetic mutation induced by 5-azacytidine and DNA-protein crosslinks in Escherichia coli
Covalent linkage between DNA and proteins produces extremely poisonous lesions and could be brought about by generally used chemotherapeutic brokers, by inside and exterior chemical substances and by radiation. In this examine, utilizing Escherichia coli, we examine the penalties of 5-azacytidine (5-azaC), which traps covalent complexes between itself and the Dcm cytosine methyltransferase protein. DNA protein crosslink-dependent results could be ascertained by results that come up in wild-type however not in dcmΔ strains.
We discover that 5-azaC induces the bacterial DNA injury response and stimulates homologous recombination, a element of which is Dcm-dependent. Template-switching at an imperfect inverted repeat (“quasipalindrome”, QP) is strongly enhanced by 5-azaC and this enhancement was fully Dcm-dependent and impartial of double-strand break restore. The SOS response helps ameliorate the mutagenic impact of 5-azaC however this isn’t a outcome of SOS-induced DNA polymerases since their induction, particularly PolIV, appears to stimulate QP-associated mutagenesis.
Cell division regulator SulA was additionally required for restoration of QP mutants induced by 5-azaC. In the absence of Lon protease, Dcm-dependent QP-mutagenesis is strongly elevated, suggesting it might play a position in DPC tolerance. Deletions at brief tandem repeats, which happen likewise by a replication template-switch, are elevated, however solely modestly, by 5-azaC. We see proof for Dcm-dependent and-independent killing by 5-azaC in delicate mutants, akin to recA, recB, and lon; homologous recombination and deletion mutations are additionally stimulated partially by a Dcm-independent impact of 5-azaC. Whether this happens by a completely different protein/DNA crosslink or by an alternate kind of DNA injury is unknown.

Pseudohypoparathyroidism Type 1A with Normocalcaemia, resulting from the Novel C.389A>G Variant of Exon 5 of the Guanine Nucleotide-Binding Protein, α-Stimulating Gene
Pseudohypoparathyroidism kind 1A (PHP1A) is a uncommon illness brought about by molecular defects in the maternally-inherited allele of the guanine nucleotide-binding protein, α-stimulating (GNAS) gene. The GNAS gene encodes the stimulatory G-protein α-subunit that regulates manufacturing of the second messenger cyclic adenosine monophosphate. Heterozygous inactivating mutations in these particular loci are liable for a spectrum of phenotypic traits of the illness, together with medical options of the Albright’s hereditary osteodystrophy, resulting from resistance to parathyroid hormone (PTH).
We report a case of PHP1A and discover the underlying novel level mutation of the GNAS gene that results in an atypical PHP1A phenotype. A male affected person with a spherical face, brief stature, and brachydactyly accompanied by normocalcaemia and delicate PTH resistance consulted at our heart. The GNAS encoding area from the affected person and each of his dad and mom have been amplified and sequenced instantly in a pattern of peripheral blood leukocytes. A novel c.389A>G level mutation in exon 5 of the GNAS gene, leading to a p.Tyr130Cys peptidic chain change of the Gsα protein, detected in the proband, in heterozygous state.
CUL1 antibody |
20R-1302 |
Fitzgerald |
100 ug |
EUR 377 |
Description: Rabbit polyclonal CUL1 antibody |
CUL1 antibody |
70R-16670 |
Fitzgerald |
50 ul |
EUR 435 |
Description: Rabbit polyclonal CUL1 antibody |
CUL1 antibody |
70R-14095 |
Fitzgerald |
100 ug |
EUR 322 |
Description: Affinity purified Rabbit polyclonal CUL1 antibody |
CUL1 Antibody |
DF6859 |
Affbiotech |
200ul |
EUR 304 |
Description: CUL1 Antibody detects endogenous levels of total CUL1. |
CUL1 Antibody |
1-CSB-PA001830 |
Cusabio |
|
|
|
Description: A polyclonal antibody against CUL1. Recognizes CUL1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000 |
CUL1 Antibody |
1-CSB-PA006218GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against CUL1. Recognizes CUL1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
CUL1 Antibody |
CSB-PA083531- |
Cusabio |
|
EUR 335 |
|
Description: A polyclonal antibody against CUL1. Recognizes CUL1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
CUL1 Antibody |
CSB-PA083531-100ul |
Cusabio |
100ul |
EUR 316 |
|
Description: A polyclonal antibody against CUL1. Recognizes CUL1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
CUL1 Antibody |
1-CSB-PA614436ESR1HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against CUL1. Recognizes CUL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:1000 |
CUL1 Antibody |
1-CSB-PA614436ESR2HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against CUL1. Recognizes CUL1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
CUL1 siRNA |
20-abx913188 |
Abbexa |
|
|
|
CUL1 siRNA |
20-abx913189 |
Abbexa |
|
|
|
CUL1 Antibody |
32618-100ul |
SAB |
100ul |
EUR 252 |
CUL1 Antibody |
43243-100ul |
SAB |
100ul |
EUR 252 |
CUL1 protein (His tag) |
80R-1515 |
Fitzgerald |
50 ug |
EUR 305 |
Description: Purified recombinant Human CUL1 protein |
CUL1 Recombinant Protein (Rat) |
RP196811 |
ABM |
100 ug |
Ask for price |
CUL1 Recombinant Protein (Mouse) |
RP126764 |
ABM |
100 ug |
Ask for price |
Human CUL1 shRNA Plasmid |
20-abx955542 |
Abbexa |
|
|
|
CUL1 Cullin-1 Human Recombinant Protein |
PROTQ13616 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: CUL1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 430 amino acids (1- 410a.a.) and having a molecular mass of 49.4kDa.;CUL1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
CUL1 Blocking Peptide |
33R-3827 |
Fitzgerald |
100 ug |
EUR 180 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CUL1 antibody, catalog no. 20R-1302 |
CUL1 Blocking Peptide |
DF6859-BP |
Affbiotech |
1mg |
EUR 195 |
CUL1 cloning plasmid |
CSB-CL614436HU1-10ug |
Cusabio |
10ug |
EUR 233 |
|
Description: A cloning plasmid for the CUL1 gene. |
CUL1 cloning plasmid |
CSB-CL614436HU2-10ug |
Cusabio |
10ug |
EUR 762 |
|
Description: A cloning plasmid for the CUL1 gene. |
CUL1 Rabbit pAb |
A2136-100ul |
Abclonal |
100 ul |
EUR 308 |
CUL1 Rabbit pAb |
A2136-200ul |
Abclonal |
200 ul |
EUR 459 |
CUL1 Rabbit pAb |
A2136-20ul |
Abclonal |
20 ul |
EUR 183 |
CUL1 Rabbit pAb |
A2136-50ul |
Abclonal |
50 ul |
EUR 223 |
CUL1 Conjugated Antibody |
C32618 |
SAB |
100ul |
EUR 397 |
anti- CUL1 antibody |
FNab02073 |
FN Test |
100µg |
EUR 505.25 |
|
Description: Antibody raised against CUL1 |
CUL1 Protein Vector (Human) (pPB-C-His) |
PV011173 |
ABM |
500 ng |
EUR 329 |
CUL1 Protein Vector (Human) (pPB-N-His) |
PV011174 |
ABM |
500 ng |
EUR 329 |
CUL1 Protein Vector (Human) (pPM-C-HA) |
PV011175 |
ABM |
500 ng |
EUR 329 |
CUL1 Protein Vector (Human) (pPM-C-His) |
PV011176 |
ABM |
500 ng |
EUR 329 |
CUL1 Protein Vector (Human) (pPB-C-His) |
PV051145 |
ABM |
500 ng |
EUR 481 |
CUL1 Protein Vector (Human) (pPB-N-His) |
PV051146 |
ABM |
500 ng |
EUR 481 |
CUL1 Protein Vector (Human) (pPM-C-HA) |
PV051147 |
ABM |
500 ng |
EUR 481 |
CUL1 Protein Vector (Human) (pPM-C-His) |
PV051148 |
ABM |
500 ng |
EUR 481 |
Recombinant Human CUL1 Protein, His, E.coli-10ug |
QP11567-10ug |
EnQuireBio |
10ug |
EUR 201 |
Recombinant Human CUL1 Protein, His, E.coli-1mg |
QP11567-1mg |
EnQuireBio |
1mg |
EUR 5251 |
Recombinant Human CUL1 Protein, His, E.coli-2ug |
QP11567-2ug |
EnQuireBio |
2ug |
EUR 155 |
CUL1 ORF Vector (Human) (pORF) |
ORF002794 |
ABM |
1.0 ug DNA |
EUR 95 |
CUL1 ORF Vector (Human) (pORF) |
ORF012787 |
ABM |
1.0 ug DNA |
EUR 354 |
Recombinant Cullin 1 (CUL1) |
4-RPC412Hu01 |
Cloud-Clone |
-
EUR 390.30
-
EUR 208.00
-
EUR 1188.64
-
EUR 462.88
-
EUR 825.76
-
EUR 324.00
-
EUR 2821.60
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
|
Description: Recombinant Human Cullin 1 expressed in: E.coli |
Cullin 1 (CUL1) Antibody |
20-abx130464 |
Abbexa |
-
EUR 425.00
-
EUR 133.00
-
EUR 1205.00
-
EUR 578.00
-
EUR 328.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Cullin 1 (CUL1) Antibody |
20-abx116818 |
Abbexa |
|
|
|
Cullin 1 (CUL1) Antibody |
20-abx320103 |
Abbexa |
|
|
|
Cullin 1 (CUL1) Antibody |
20-abx321517 |
Abbexa |
|
|
|
Mouse CUL1 shRNA Plasmid |
20-abx973806 |
Abbexa |
|
|
|
Cullin 1 (CUL1) Antibody |
abx232073-100ug |
Abbexa |
100 ug |
EUR 481 |
|
Cullin 1 (CUL1) Antibody |
abx331499-100ul |
Abbexa |
100 ul |
EUR 425 |
|
Cullin 1 (CUL1) Antibody |
20-abx326122 |
Abbexa |
|
|
|
Cullin 1 (CUL1) Antibody |
20-abx001748 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 182.00
-
EUR 314.00
|
-
100 ul
-
200 ul
-
20 ul
-
50 ul
|
|
Cullin 1 (CUL1) Antibody |
abx037825-100ug |
Abbexa |
100 ug |
EUR 391 |
|
Cullin 1 (CUL1) Antibody |
20-abx008528 |
Abbexa |
-
EUR 300.00
-
EUR 439.00
-
EUR 189.00
|
|
|
Cullin 1 (CUL1) Antibody |
20-abx013050 |
Abbexa |
-
EUR 314.00
-
EUR 98.00
-
EUR 398.00
-
EUR 495.00
|
-
100 ug
-
10 ug
-
200 ug
-
300 µg
|
|
Cullin 1 (CUL1) Antibody |
abx028739-400ul |
Abbexa |
400 ul |
EUR 523 |
|
Cullin 1 (CUL1) Antibody |
abx028739-80l |
Abbexa |
80 µl |
EUR 286 |
|
Human Cullin 1(CUL1) ELISA kit |
E01C2181-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Human Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Cullin 1(CUL1) ELISA kit |
E01C2181-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Human Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Cullin 1(CUL1) ELISA kit |
E01C2181-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Human Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Cullin 1 (CUL1) Polyclonal Antibody (Human) |
4-PAC412Hu01 |
Cloud-Clone |
-
EUR 247.00
-
EUR 2510.00
-
EUR 625.00
-
EUR 310.00
-
EUR 214.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Human Cullin 1 (CUL1) |
CUL1 sgRNA CRISPR Lentivector set (Human) |
K0532301 |
ABM |
3 x 1.0 ug |
EUR 339 |
Human Cullin 1 (CUL1) ELISA Kit |
abx386735-96tests |
Abbexa |
96 tests |
EUR 911 |
|
CUL1 Protein Vector (Mouse) (pPB-C-His) |
PV169022 |
ABM |
500 ng |
EUR 1065 |
CUL1 Protein Vector (Mouse) (pPB-N-His) |
PV169023 |
ABM |
500 ng |
EUR 1065 |
CUL1 Protein Vector (Mouse) (pPM-C-HA) |
PV169024 |
ABM |
500 ng |
EUR 1065 |
CUL1 Protein Vector (Mouse) (pPM-C-His) |
PV169025 |
ABM |
500 ng |
EUR 1065 |
CUL1 Protein Vector (Rat) (pPB-C-His) |
PV262418 |
ABM |
500 ng |
EUR 1166 |
CUL1 Protein Vector (Rat) (pPB-N-His) |
PV262419 |
ABM |
500 ng |
EUR 1166 |
CUL1 Protein Vector (Rat) (pPM-C-HA) |
PV262420 |
ABM |
500 ng |
EUR 1166 |
CUL1 Protein Vector (Rat) (pPM-C-His) |
PV262421 |
ABM |
500 ng |
EUR 1166 |
Cullin 1 (CUL1) Polyclonal Antibody (Human), APC |
4-PAC412Hu01-APC |
Cloud-Clone |
-
EUR 345.00
-
EUR 3275.00
-
EUR 912.00
-
EUR 440.00
-
EUR 219.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Human Cullin 1 (CUL1). This antibody is labeled with APC. |
Cullin 1 (CUL1) Polyclonal Antibody (Human), Biotinylated |
4-PAC412Hu01-Biotin |
Cloud-Clone |
-
EUR 311.00
-
EUR 2460.00
-
EUR 727.00
-
EUR 381.00
-
EUR 219.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Human Cullin 1 (CUL1). This antibody is labeled with Biotin. |
Cullin 1 (CUL1) Polyclonal Antibody (Human), Cy3 |
4-PAC412Hu01-Cy3 |
Cloud-Clone |
-
EUR 419.00
-
EUR 4325.00
-
EUR 1175.00
-
EUR 545.00
-
EUR 251.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Human Cullin 1 (CUL1). This antibody is labeled with Cy3. |
Cullin 1 (CUL1) Polyclonal Antibody (Human), FITC |
4-PAC412Hu01-FITC |
Cloud-Clone |
-
EUR 296.00
-
EUR 2640.00
-
EUR 750.00
-
EUR 372.00
-
EUR 195.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Human Cullin 1 (CUL1). This antibody is labeled with FITC. |
Cullin 1 (CUL1) Polyclonal Antibody (Human), HRP |
4-PAC412Hu01-HRP |
Cloud-Clone |
-
EUR 316.00
-
EUR 2855.00
-
EUR 807.00
-
EUR 398.00
-
EUR 206.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Human Cullin 1 (CUL1). This antibody is labeled with HRP. |
Cullin 1 (CUL1) Polyclonal Antibody (Human), PE |
4-PAC412Hu01-PE |
Cloud-Clone |
-
EUR 296.00
-
EUR 2640.00
-
EUR 750.00
-
EUR 372.00
-
EUR 195.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Human Cullin 1 (CUL1). This antibody is labeled with PE. |
CUL1 sgRNA CRISPR Lentivector (Human) (Target 1) |
K0532302 |
ABM |
1.0 ug DNA |
EUR 154 |
CUL1 sgRNA CRISPR Lentivector (Human) (Target 2) |
K0532303 |
ABM |
1.0 ug DNA |
EUR 154 |
CUL1 sgRNA CRISPR Lentivector (Human) (Target 3) |
K0532304 |
ABM |
1.0 ug DNA |
EUR 154 |
Cul1 ORF Vector (Rat) (pORF) |
ORF065605 |
ABM |
1.0 ug DNA |
EUR 506 |
Cul1 ORF Vector (Mouse) (pORF) |
ORF042256 |
ABM |
1.0 ug DNA |
EUR 506 |
Anti-Cullin 1/Cul1 Antibody |
PA1557 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-Cullin 1/CUL1 Antibody |
PB9542 |
BosterBio |
100ug/vial |
EUR 294 |
Recombinant Schizosaccharomyces Pombe cul1 Protein (aa 1-767) |
VAng-Yyj5643-inquire |
Creative Biolabs |
inquire |
Ask for price |
Description: Schizosaccharomyces Pombe (strain 972 / ATCC 24843) (Fission yeast) Cullin-1 (cul1), partial, recombinant protein. |
Cullin 1 (CUL1) Polyclonal Antibody (Human), APC-Cy7 |
4-PAC412Hu01-APC-Cy7 |
Cloud-Clone |
-
EUR 571.00
-
EUR 6430.00
-
EUR 1705.00
-
EUR 760.00
-
EUR 319.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Human Cullin 1 (CUL1). This antibody is labeled with APC-Cy7. |
CUL1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
LV704097 |
ABM |
1.0 ug DNA |
EUR 450 |
CUL1 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC) |
LV704101 |
ABM |
1.0 ug DNA |
EUR 450 |
CUL1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a) |
LV704102 |
ABM |
1.0 ug DNA |
EUR 450 |
Rat Cullin 1(CUL1) ELISA kit |
E02C2181-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Rat Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Cullin 1(CUL1) ELISA kit |
E02C2181-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Rat Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Cullin 1(CUL1) ELISA kit |
E02C2181-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Rat Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Cullin 1(CUL1) ELISA kit |
E03C2181-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Cullin 1(CUL1) ELISA kit |
E03C2181-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Cullin 1(CUL1) ELISA kit |
E03C2181-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Cullin 1(CUL1) ELISA kit |
E04C2181-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Cullin 1(CUL1) ELISA kit |
E04C2181-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Cullin 1(CUL1) ELISA kit |
E04C2181-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Cullin 1(CUL1) ELISA kit |
E09C2181-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Cullin 1(CUL1) ELISA kit |
E09C2181-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Cullin 1(CUL1) ELISA kit |
E09C2181-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Cul1 sgRNA CRISPR Lentivector set (Mouse) |
K4984601 |
ABM |
3 x 1.0 ug |
EUR 339 |
Cul1 sgRNA CRISPR Lentivector set (Rat) |
K6613601 |
ABM |
3 x 1.0 ug |
EUR 339 |
Dog Cullin 1(CUL1) ELISA kit |
E08C2181-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Canine Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Cullin 1(CUL1) ELISA kit |
E08C2181-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Canine Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Cullin 1(CUL1) ELISA kit |
E08C2181-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Canine Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Cullin 1(CUL1) ELISA kit |
E07C2181-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Cullin 1(CUL1) ELISA kit |
E07C2181-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Cullin 1(CUL1) ELISA kit |
E07C2181-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Cullin 1(CUL1) ELISA kit |
E06C2181-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Goat Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Cullin 1(CUL1) ELISA kit |
E06C2181-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Goat Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Cullin 1(CUL1) ELISA kit |
E06C2181-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Goat Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
CUL1 3'UTR Luciferase Stable Cell Line |
TU005276 |
ABM |
1.0 ml |
EUR 4617 |
Cul1 3'UTR GFP Stable Cell Line |
TU154552 |
ABM |
1.0 ml |
Ask for price |
Cul1 3'UTR Luciferase Stable Cell Line |
TU104552 |
ABM |
1.0 ml |
Ask for price |
Cul1 3'UTR Luciferase Stable Cell Line |
TU202964 |
ABM |
1.0 ml |
Ask for price |
Cul1 3'UTR GFP Stable Cell Line |
TU252964 |
ABM |
1.0 ml |
Ask for price |
CUL1 3'UTR GFP Stable Cell Line |
TU055276 |
ABM |
1.0 ml |
EUR 4617 |
Cul1 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K4984602 |
ABM |
1.0 ug DNA |
EUR 154 |
Cul1 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K4984603 |
ABM |
1.0 ug DNA |
EUR 154 |
Cul1 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K4984604 |
ABM |
1.0 ug DNA |
EUR 154 |
Cul1 sgRNA CRISPR Lentivector (Rat) (Target 1) |
K6613602 |
ABM |
1.0 ug DNA |
EUR 154 |
Cul1 sgRNA CRISPR Lentivector (Rat) (Target 2) |
K6613603 |
ABM |
1.0 ug DNA |
EUR 154 |
Cul1 sgRNA CRISPR Lentivector (Rat) (Target 3) |
K6613604 |
ABM |
1.0 ug DNA |
EUR 154 |
Guinea pig Cullin 1(CUL1) ELISA kit |
E05C2181-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Cullin 1(CUL1) ELISA kit |
E05C2181-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Cullin 1(CUL1) ELISA kit |
E05C2181-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig Cullin 1(CUL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Polyclonal Cullin 1 / CUL1 Antibody (C-Terminus) |
APR02207G |
Leading Biology |
0.05ml |
EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cullin 1 / CUL1 (C-Terminus). This antibody is tested and proven to work in the following applications: |
Polyclonal Cullin 1 / CUL1 Antibody (aa727-776) |
APR02922G |
Leading Biology |
0.05ml |
EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cullin 1 / CUL1 (aa727-776). This antibody is tested and proven to work in the following applications: |
CUL1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
K0532305 |
ABM |
3 x 1.0 ug |
EUR 376 |
CUL1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV) |
LV620887 |
ABM |
1.0 ug DNA |
EUR 1355 |
CUL1 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC) |
LV620891 |
ABM |
1.0 ug DNA |
EUR 1355 |
CUL1 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a) |
LV620892 |
ABM |
1.0 ug DNA |
EUR 1355 |
CUL1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA) |
LV704098 |
ABM |
1.0 ug DNA |
EUR 450 |
Sequencing of the GNAS gene from his dad and mom didn’t reveal the c.389A>G mutation, confirming a de novo proband genotype. The maternal origin of the affected GNAS allele, together with delicate PTH resistance, confirmed the PHP1A prognosis. PHP1A, brought about by inactivating GNAS mutations, presents a vary of advanced medical phenotypes. The novel c.389A>G GNAS mutation introduced on this case expands the spectrum of identified PHP1A molecular defects and describes the related phenotype.