Gene variants of coagulation related proteins that interact with SARS-CoV-2

Thrombosis is a acknowledged complication of Coronavirus illness of 2019 (COVID-19) sickness and is commonly related with poor prognosis. There is a well-recognized hyperlink between coagulation and irritation, nonetheless, the extent of thrombotic occasions related with COVID-19 warrants additional investigation. Poly(A) Binding Protein Cytoplasmic 4 (PABPC4), Serine/Cysteine Proteinase Inhibitor Clade G Member 1 (SERPING1) and Vitamin Ok epOxide Reductase Complex subunit 1 (VKORC1), that are all proteins linked to coagulation, have been proven to interact with SARS proteins. We computationally examined the interplay of these with SARS-CoV-2 proteins and, within the case of VKORC1, we describe its binding to ORF7a intimately.

We examined the prevalence of variants of every of these proteins throughout populations and interrogated their potential contribution to COVID-19 severity. Potential mechanisms, by which some of these variants could contribute to illness, are proposed. Some of these variants are prevalent in minority teams that are disproportionally affected by extreme COVID-19. Therefore, we’re proposing that additional investigation round these variants could result in higher understanding of illness pathogenesis in minority teams and extra knowledgeable therapeutic approaches.

We carry out a complete, high-throughput display screen of this library, utilizing Caenorhabditis elegans as a simplified mannequin host system, which recognized mutants important for virulence and vital genetic interactions. We carry out follow-up evaluation to evaluate the flexibility of high- and low-virulence strains to endure mobile morphogenesis and type biofilms in vitro, in addition to to colonize the C. elegans host. We additional carry out genetic interplay evaluation to determine novel vital unfavourable genetic interactions between adhesin mutants, whereby combinatorial perturbation of these genes considerably impairs virulence, greater than anticipated based mostly on virulence of the only mutant constituent strains.

Candida albicans is a microbial fungus that exists as a commensal member of the human microbiome and an opportunistic pathogen. Cell surface-associated adhesin proteins play a vital function in C. albicans’ means to endure mobile morphogenesis, develop sturdy biofilms, colonize, and trigger an infection in a number. However, a complete evaluation of the function and relationships between these adhesins has not been explored. We beforehand established a CRISPR-based platform for environment friendly era of single- and double-gene deletions in C. albicans, which was used to assemble a library of 144 mutants, comprising 12 distinctive adhesin genes deleted singly, and each potential mixture of double deletions. Here, we exploit this adhesin mutant library to discover the function of adhesin proteins in C. albicans virulence.

A heterochromatin inducing protein differentially acknowledges self versus international genomes

Krüppel-associated box-domain zinc finger protein (KRAB-ZFP) transcriptional repressors recruit TRIM28/KAP1 to heterochromatinize the mammalian genome whereas additionally guarding the host by silencing invading international genomes. However, how a KRAB-ZFP acknowledges goal sequences within the pure context of its personal or international genomes is unclear. Our research on B-lymphocytes completely harboring the cancer-causing Epstein-Barr virus (EBV) have proven that SZF1, a KRAB-ZFP, binds to a number of lytic/replicative part genes to silence them, thereby selling the latent/quiescent part of the virus.

As a end result, until SZF1 and its binding companions are displaced from goal areas on the viral genome, EBV stays dormant, i.e. refractory to lytic phase-inducing triggers. As SZF1 additionally heterochromatinizes the mobile genome, we carried out in situ-footprint mapping on each viral and host genomes in bodily separated B-lymphocytes bearing latent or replicative/energetic EBV genomes. By analyzing footprints, we discovered that SZF1 acknowledges the host genome by way of a repeat sequence-bearing motif close to centromeres. Remarkably, SZF1 doesn’t use this motif to acknowledge the EBV genome.

Instead, it makes use of distinct binding websites that lack apparent similarities to one another or the above motif, to silence the viral genome. Virus mutagenesis research present that these distinct binding websites are usually not solely key to sustaining the established latent part but additionally silencing the lytic part in newly-infected cells, thus enabling the virus to determine latency and remodel cells. Notably, these binding websites on the viral genome, when additionally current on the human genome, are usually not utilized by SZF1 to silence host genes throughout latency. This differential strategy in the direction of goal website recognition could replicate a method by which the host silences and regulates genomes of persistent invaders with out jeopardizing its personal homeostasis.

Gene variants of coagulation related proteins that interact with SARS-CoV-2

Identification of Protein Direct Interactome with Genetic Code Expansion and Search Engine OpenUaa

Protein crosslinks happen endogenously equivalent to modifications by ubiquitin-like proteins for signaling, or exogenously by way of genetically encoded chemical crosslinkers (GECX) for learning elusive protein-protein interactions. However, it stays difficult to determine these protein crosslinks effectively on the proteomic scale. Herein, software program OpenUaa is developed for figuring out protein crosslinks generated by genetically encoded unnatural amino acids and endogenous protein conjugation.

OpenUaa options inclusive and open search functionality, dramatically enhancing identification sensitivity and protection. Integrating GECX with OpenUaa, the direct interactome of thioredoxin is recognized in Escherichia coli cells, yielding 289 crosslinked peptides and comparable to 205 direct binding protein of thioredoxin. Together, this examine yields necessary new perception into the function of adhesins, singly and in combos, in mediating various sides of virulence of this important fungal pathogen.

Cullin 3 antibody

70R-12743 100 ul
EUR 457
Description: Affinity purified Rabbit polyclonal Cullin 3 antibody

Cullin-3 Conjugated Antibody

C48517 100ul
EUR 397

Polyclonal Cullin 3 Antibody

APR05518G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cullin 3 . This antibody is tested and proven to work in the following applications:

Cullin 3 (CUL3) Antibody

20-abx116820
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 3 (CUL3) Antibody

abx122597-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Cullin 3 (CUL3) Antibody

20-abx001001
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 3 (CUL3) Antibody

20-abx008530
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Cullin 3 (CUL3) Antibody

20-abx325304
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Cullin 3 (CUL3) Antibody

20-abx214183
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 3 (CUL3) Antibody

abx432557-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Cullin 3 (CUL3) Antibody

abx232075-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Anti-Cullin 3 antibody

STJ73313 100 µg
EUR 359

anti-Cullin 3

LF-PA0247 100 ul
EUR 334
Description: Rabbit polyclonal to Cullin 3

Cullin 3 recombinant monoclonal antibody

A5966 100ul X 3
EUR 595
  • Comparisons between Mnoclonal, Polyclonal and Recombinant antibodies and their benefits: Regular monoclonal antibodies have higher purity, better specificity and less lot-to-lot variations than polyclonal antibodies. Recombinant antibodies, however,
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Description: A recombinant monoclonal antibody from rabbit against human Cullin 3 for WB, IF,ELISA

Anti-Cullin 3 Monoclonal Antibody

M00747 100ug
EUR 397
Description: Rabbit Monoclonal Cullin 3 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat.

Anti-Cullin 3/CUL3 Antibody

PA1939 100ug/vial
EUR 294

Cullin 1 Antibody

AF0140 200ul
EUR 304
Description: Cullin 1 antibody detects endogenous levels of total Cullin 1.

Cullin 2 Antibody

AF0141 200ul
EUR 304
Description: Cullin 2 antibody detects endogenous levels of total Cullin 2.

Cullin 1 Antibody

ABF0140 100 ug
EUR 438

Cullin 2 Antibody

ABF0141 100 ug
EUR 438

Cullin 2 antibody

70R-50597 100 ul
EUR 244
Description: Purified Polyclonal Cullin 2 antibody

Cullin 1 antibody

70R-50598 100 ul
EUR 244
Description: Purified Polyclonal Cullin 1 antibody

Cullin 1 antibody

70R-31147 100 ug
EUR 327
Description: Rabbit polyclonal Cullin 1 antibody

Cullin 2 antibody

70R-31148 100 ug
EUR 327
Description: Rabbit polyclonal Cullin 2 antibody

Cullin 1 Antibody

49672-100ul 100ul
EUR 333

Cullin 1 Antibody

49672-50ul 50ul
EUR 239

Cullin 4a Antibody

49742-100ul 100ul
EUR 333

Cullin 4a Antibody

49742-50ul 50ul
EUR 239

Cullin 2 Antibody

49917-100ul 100ul
EUR 333

Cullin 2 Antibody

49917-50ul 50ul
EUR 239

Cullin 1 Antibody

33347-100ul 100ul
EUR 252

Cullin 1 Antibody

33347-50ul 50ul
EUR 187

Cullin 2 Antibody

33348-100ul 100ul
EUR 252

Cullin 2 Antibody

33348-50ul 50ul
EUR 187

Cullin-7 antibody

22865-100ul 100ul
EUR 390

Cullin 5 antibody

70R-12901 100 ul
EUR 457
Description: Affinity purified Rabbit polyclonal Cullin 5 antibody

Cullin 7 antibody

70R-13573 100 ul
EUR 457
Description: Affinity purified Rabbit polyclonal Cullin 7 antibody

Cullin 5 antibody

70R-1629 100 ug
EUR 377
Description: Rabbit polyclonal Cullin 5 antibody raised against the C terminal of CUL5

Cullin 3 Blocking Peptide

20-abx063471
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.

Cullin 3 Rabbit mAb

A19623-100ul 100 ul
EUR 410

Cullin 3 Rabbit mAb

A19623-200ul 200 ul
EUR 571

Cullin 3 Rabbit mAb

A19623-20ul 20 ul
EUR 221

Cullin 3 Rabbit mAb

A19623-50ul 50 ul
EUR 287

Recombinant Human Cullin-3

7-04950 1mg Ask for price

Anti-Cullin 3 (1A3)

YF-MA16361 100 ug
EUR 363
Description: Mouse monoclonal to Cullin 3

Polyclonal Cullin 3 Antibody (internal region)

APG00564G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Cullin 3 (internal region). This antibody is tested and proven to work in the following applications:

Polyclonal Cullin 3 / CUL3 Antibody (N-Terminus)

APR02209G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cullin 3 / CUL3 (N-Terminus). This antibody is tested and proven to work in the following applications:

Polyclonal Cullin 3 / CUL3 Antibody (aa293-554)

APR03329G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cullin 3 / CUL3 (aa293-554). This antibody is tested and proven to work in the following applications:

Cullin 1 Conjugated Antibody

C49672 100ul
EUR 397

Cullin 4a Conjugated Antibody

C49742 100ul
EUR 397

Cullin 2 Conjugated Antibody

C49917 100ul
EUR 397

Polyclonal Cullin 2 Antibody

APR05401G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cullin 2 . This antibody is tested and proven to work in the following applications:

Polyclonal Cullin 1 Antibody

APR05405G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cullin 1 . This antibody is tested and proven to work in the following applications:

Cullin 1 Conjugated Antibody

C33347 100ul
EUR 397

Cullin 2 Conjugated Antibody

C33348 100ul
EUR 397

Cullin 1 (CUL1) Antibody

20-abx116818
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

20-abx116819
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4A (CUL4A) Antibody

20-abx116821
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

20-abx116822
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 7 (CUL7) Antibody

20-abx116823
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 9 (CUL9) Antibody

20-abx129204
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Cullin 1 (CUL1) Antibody

20-abx130464
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Cullin 4A (CUL4A) Antibody

abx122598-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

abx122599-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

abx122600-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

20-abx001748
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4A (CUL4A) Antibody

20-abx002116
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

20-abx141193
  • EUR 356.00
  • EUR 537.00
  • EUR 217.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

abx037823-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

abx037824-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

abx037825-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

abx033487-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

abx033487-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

20-abx008528
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

20-abx008529
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

20-abx013050
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

20-abx013051
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

20-abx007275
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

abx023909-01ml 0.1 ml
EUR 1052
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

abx023911-01ml 0.1 ml
EUR 1052
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

20-abx004058
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

20-abx004110
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

20-abx004135
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

20-abx004735
  • EUR 495.00
  • EUR 356.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4A (CUL4A) Antibody

20-abx004736
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

abx031459-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

abx031459-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Cullin 4A (CUL4A) Antibody

abx027660-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Cullin 4A (CUL4A) Antibody

abx027660-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

abx028739-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

abx028739-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

20-abx326122
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

20-abx326123
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

20-abx320103
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

20-abx320142
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

20-abx320143
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

20-abx320340
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

20-abx321517
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

20-abx327540
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

abx331499-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

abx331500-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

abx432148-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Cullin 7 (CUL7) Antibody

20-abx242467
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 7 (CUL7) Antibody

20-abx242540
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4A (CUL4A) Antibody

20-abx301106
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

20-abx302533
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

20-abx212055
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4B (CUL4B) Antibody

20-abx212968
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 2 (CUL2) Antibody

20-abx213537
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4A (CUL4A) Antibody

20-abx213538
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

20-abx213650
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 4A (CUL4A) Antibody

20-abx225131
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 5 (CUL5) Antibody

20-abx225132
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cullin 1 (CUL1) Antibody

abx232073-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Cullin 2 (CUL2) Antibody

abx232074-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Cullin 4A (CUL4A) Antibody

abx232076-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Cullin 4A (CUL4A) Antibody

abx232077-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Cullin 4B (CUL4B) Antibody

abx232079-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Cullin 4B (CUL4B) Antibody

abx232080-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Cullin 7 (CUL7) Antibody

abx232081-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Cullin 9 (CUL9) Antibody

20-abx171965
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.

Anti-Cullin 5 antibody

STJ13100099 100 µl
EUR 427

Anti-14-3-3 alpha + beta Rabbit Monoclonal Antibody

M02431-3 100ug/vial
EUR 397
Description: Rabbit Monoclonal 14-3-3 alpha + beta Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Rabbit Anti-Cullin3 (Cullin-3, Cul 3)

Ab5152 100ug
EUR 556

Anti-VEGF Receptor 3/FLT4 Antibody

A01276-3 100ug/vial
EUR 334

Goat Cullin 3(CUL3) ELISA kit

E06C2183-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Cullin 3(CUL3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Cullin 3(CUL3) ELISA kit

E06C2183-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Cullin 3(CUL3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Cullin 3(CUL3) ELISA kit

E06C2183-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Cullin 3(CUL3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Cullin 3(CUL3) ELISA kit

E01C2183-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human Cullin 3(CUL3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Cullin 3(CUL3) ELISA kit

E01C2183-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human Cullin 3(CUL3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Cullin 3(CUL3) ELISA kit

E01C2183-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Cullin 3(CUL3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

These recognized direct binders present proof for thioredoxin’s regulation of redox state and mitochondria vitality metabolism. When figuring out endogenous conjugation of small ubiquitin-like modifier (SUMO), OpenUaa additionally markedly improves protection of SUMOylated peptides by ≈92%, revealing new SUMO targets. GECX-OpenUaa will allow environment friendly identification of direct interactomes of varied proteins in stay cells.

Glenda Montgomery

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