Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase

The Forkhead box m1 (Foxm1) gene is crucial for G(1)/S transition and essential for mitotic progression. However, the transcriptional mechanisms downstream of FoxM1 that management these cell cycle occasions stay to be decided. Here, we present that each early-passage Foxm1(-)(/)(-) mouse embryonic fibroblasts (MEFs)…